Here are some hints when 'scanning' negatives with an Olympus OM-D EM-5 digital camera with 60mm macro lens.

• Photograph back side (emulsion)

• Largest ratio for sensor (3:2)
• Base ISO (200)
• IS off
• Sharpening & Noise filter off
• Whitebalance (white) in camera on blank film
• Zuiko 60mm MACRO at f/4
• Shutterspeed: 1/125

• FL600R
• Intensity: 1/128 (for lens at f/4)

• Rotate
• Invert image (curve)
• Sharpening 0
• Noise reduction 0
• Convert to grayscale (Default, not auto)
• Camera profile: Camera Neutral

• Proof colors: Ctl-y
• Proof setup: Monitor RGB
• Set correct DPI (for 100% view)
• Image grayscale
• 16bit

• Aperture of lens did have great effect.
• Photographing emulsion side had a marginal effect (better).
• Stacking 10 imgages did not reduce noise, so it probably is grain (clusters).
• Noise filter didn't have a real effect (leave it to off).
• Green channel from raw file gives most detail.